Forma Medical WellnessTestosterone safety
Testosterone replacement therapy (TRT) is for men with clinically low testosterone confirmed by lab testing. It requires ongoing monitoring — here's who it's for and what to watch for.
Testosterone
testosterone (injection, gel, or cream)Injection, topical gel, or cream
TRT restores testosterone to a healthy range in men whose bodies don't produce enough (hypogonadism), which can support energy, libido, mood, muscle mass, and bone density.
Secondary exposure (topical forms): Children and women can be harmed by contact with testosterone gel/cream on your skin. Wash hands, cover the application site, and avoid skin-to-skin contact until absorbed. Blood pressure can also increase, raising cardiovascular risk.
What it treats
- Primary hypogonadism (testicular failure) with confirmed low testosterone
- Hypogonadotropic hypogonadism (a problem with brain signaling) with confirmed low testosterone
- Symptoms such as low energy, low libido, or reduced muscle mass together with lab-confirmed low levels
Who shouldn't take it
- Known or suspected prostate cancer
- Known or suspected male breast cancer
- Women, especially those who are or may become pregnant or breastfeeding
- Known hypersensitivity to testosterone or the formulation
Warnings & precautions
- Increased red blood cell count (polycythemia) — requires periodic blood monitoring
- May increase the risk of cardiovascular events in some men
- Can worsen benign prostatic hyperplasia (urinary) symptoms
- May worsen sleep apnea
- Reduces sperm production and can impair fertility
- Not for boosting performance or for men with normal testosterone levels
Common side effects
- Acne or oily skin
- Injection-site or application-site reactions
- Increased red blood cell count
- Mood changes
- Fluid retention (swelling)
Call your clinician if you notice
- Chest pain, shortness of breath, or signs of a blood clot (leg pain/swelling)
- Difficulty urinating or worsening urinary symptoms
- Prolonged or painful erections
Ready to see if this fits you?
Start Your IntakeThis information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. A licensed Forma clinician will review your health history and current medications to determine whether treatment is safe and appropriate for you. Never start, stop, or change a prescription without talking to a healthcare provider. If you think you may have a medical emergency, call 911.